Radial glial cell

Radial glial cells are bipolar-shaped cells that span the width of the cortex in the developing central nervous system (CNS) and serve as primary progenitor cells capable of generating neurons, astrocytes, and oligodendrocytes. During development, newborn neurons use radial glia as scaffolds, traveling along the radial glial fibers in order to reach their final destinations. Despite the various possible fates of the radial glial population, it has been demonstrated through clonal analysis that most radial glia have restricted, unipotent or multipotent, fates. Radial glia can be found during the neurogenic phase in all vertebrates (studied to date).