A.C.E. mixture

A.C.E. mixture (or ACE mixture) is a historical anaesthetic agent for general anaesthesia. It was first suggested by Dr. George Harley and first used in England around 1860. In 1864 it was recommended for use by the Royal Medical and Surgical Society’s Chloroform Committee. It was rarely used after the 19th century, except in Germany, where it was used for slightly longer.