And this is called forced diuresis and it essentially overwhelms the proximal convoluted tubule of the nephron with so much fluid that it's unable to effectively reabsorb solutes, including phosphate.

这叫强迫利尿，它会使近曲小管充盈大量液体，以至于不能有效地重新吸收溶质，包括磷酸盐。

These two make their way to the nephron of the kidney, and at this point in the proximal convoluted tubule, phosphate usually gets reabsorbed back into the blood via sodium-phosphate cotransporters.

随着这一对离子进入肾脏的肾单位之中，在近曲小管处，磷酸盐通常被重新吸收，经由钠-磷协同转运蛋白重新入血。

After that, about 67% is reabsorbed in the proximal convoluted tubule, and an additional 20% is reabsorbed in the thick ascending limb, and that leaves about 13% of the initial amount, right?

之后，其中大概67%在近曲小管被重吸收，另外还有20%在粗支升段被重吸收，所以只剩下了原始量的13%，对吧。

Now, these two make their way to the nephron of the kidney, and at this point in the proximal convoluted tubule, phosphate usually gets reabsorbed back into the blood via sodium-phosphate cotransporters.

接下来，他们到达了肾小管的肾单位处，在近曲小管的这里，磷酸盐常通过钠-磷协转运蛋白被重新吸收到血液中。

Another example is Fanconi syndrome, which is where the proximal convoluted tubule essentially loses its capacity to reabsorb a variety of solutes - including phosphate - once again letting it get excreted in the urine.

另一个例子是范可尼综合征，即近曲小管基本上失去了重新吸收各种溶质（包括磷酸盐）的能力，导致磷酸盐通过尿液排出。