普莱西诉弗格森案（英语：Plessy v. Ferguson），有时简称“普莱西案”，是美国历史上一个标志性案件，这个判决维护了种族隔离的合法性，使得美国南部各州在公共场合实施的“隔离但平等”的种族隔离法延续了半个多世纪，直到1954年最高法院判决布朗诉托皮卡教育局案以及此后国会于1964年通过的民权法、1965年通过的投票权法（Voting Rights Act of 1965）后，南部各州实施的种族隔离法才彻底消失。

Plessy v. Ferguson, 163 U.S.537(1896), was a landmark United States Supreme Court decision upholding the constitutionality of state laws requiring racial segregation in public facilities under the doctrine of "separate but equal". The decision was handed down by a vote of 7 to 1 with the majority opinion written by Justice Henry Billings Brown and the dissent written by Justice John Marshall Harlan.