Phrenitis
![A horse with phrenitis, 1678. Lld manuscript from the Deutsche Fotothek](/Images/godic/202502/02/Fotothek_df_tg_0005622_Nutztierhaltung_^_Tiermedizin_^_Pferd_^_Krankheit0541.jpg")
The term phrenitis was employed in ancient Greece by Hippocrates and his followers. It refers to acute inflammation of mind and body, not in a theoretical but in a descriptive sense. Its presumed seat was never anatomically or conceptually well determined. The diagnosis was used during the Middle Ages: a mental confusion or continuous delirium with fever.