Phosphoribosylglycinamide formyltransferase
![](/Images/godic/202502/02/PDB_1rbm_EBI0636.jpg")
![Structure of GAR transformylase in rainbow from N(blue)->C(red). Folate binding loop is highlighted in black. GAR substrate (red) and THF analogue (blue) are shown in binding pockets.[9]](/Images/godic/202502/02/GAR_transformylase0636.png")
![GAR transformylase water assisted mechanism suggested by Qiao et al](/Images/godic/202502/02/GAR_transformylase_mechanism_suggested_by_Qiao_et_al0636.jpg")
Phosphoribosylglycinamide formyltransferase (EC2.1.2.2, 2-amino-N-ribosylacetamide 5'-phosphate transformylase, GAR formyltransferase, GAR transformylase, glycinamide ribonucleotide transformylase, GAR TFase, 5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase) is an enzyme with systematic name 10-formyltetrahydrofolate:5'-phosphoribosylglycinamide N-formyltransferase. This enzyme catalyses the following chemical reaction