Ribose-5-phosphate isomerase
（重定向自Phosphopentose isomerase）
![A structural diagram of the enzyme ribose-5-phosphate isomerase by Zhang, et al.](/Images/godic/202502/02/Ribose-5-phosphate_isomerase0134.png")
![](/Images/godic/202502/02/Mech_20134.png")
![](/Images/godic/202502/02/Final-_calvin_and_PPP0134.JPG")
Ribose-5-phosphate isomerase (Rpi) is an enzyme that catalyzes the conversion between ribose-5-phosphate (R5P) and ribulose-5-phosphate (Ru5P). It is a member or a larger class of isomerases which catalyze the interconversion of chemical isomers (in this case structural isomers of pentose). It plays a vital role in biochemical metabolism in both the pentose phosphate pathway and the Calvin cycle. The systematic name of this enzyme class is D-ribose-5-phosphate aldose-ketose-isomerase.