11-Beta hydroxysteroid dehydrogenase
![Cortisol. Note the OH at the 11 position on ring C. (The other differences between the diagrams are not of consequence.)](/Images/godic/202412/12/Cortisol2.svg0303.png")
![Cortisone](/Images/godic/202412/12/Cortison.svg0303.png")
11β-Hydroxysteroid dehydrogenase (HSD-11β or 11β-HSD) is the name of a family of enzymes that catalyze the conversion of inert 11 keto-products (cortisone) to active cortisol, or vice versa, thus regulating the access of glucocorticoids to the steroid receptors: