Palo Grande is a corregimiento in Alanje District, Chiriquí Province, Panama. It has a land area of 41 square kilometres (16 sq mi) and had a population of 578 as of 2010, giving it a population density of 14.1 inhabitants per square kilometre (37/sq mi). Its population as of 1990 was 563; its population as of 2000 was 563.