大国主是日本神话中在出云神话出现的国津神。

大国主拥有许多别名：

Ōkuninushi (大国主) is a divinity (kami) in Japanese Shinto. His name literally translates to "Great Land Master", and he is believed to be originally the ruler of Izumo Province, until he was replaced by Ninigi. In compensation, he was made ruler of the unseen world of spirits and magic. He is believed to be a god of nation-building, farming, business, and medicine.