Myelofibrosis with myeloid metaplasia:pathophysiologic implications of the correlation between bone marrow changes and progression of splenomegaly. 慢性特发性骨髓纤维化病理分型与临床预后的关系。
In rare cases, essential thrombocythemia can develop into myelofibrosis and acute leukemia.
少数原发性血小板增多症案例会发展为骨髓纤维化或急性白血病。
英语百科
Myelofibrosis
Myelofibrosis, also known as osteomyelofibrosis, is a rare bone marrow cancer. It is currently classified as a myeloproliferative neoplasm, in which the proliferation of an abnormal clone of hematopoietic stem cells in the bone marrow and other sites results in fibrosis, or the replacement of the marrow with scar tissue.