Mutt and Jeff

Mutt and Jeff is a long-running and widely popular American newspaper comic strip created by cartoonist Bud Fisher in 1907 about "two mismatched tinhorns." Historians regard Mutt and Jeff, originally entitled A. Mutt, as the first American newspaper cartoon published as a strip of panels, as opposed to a single panel, making it the first "comic strip" to successfully pioneer that since-common format.