莫卡辛鞋（Moccasin），或称为鹿皮鞋，是一种由鹿皮或其他软皮制成的鞋，穿起来柔软而灵便。其前半部分通常有刺绣或其他装饰物。莫卡辛鞋一般都是直接穿在外面的，但偶尔也会被穿在另外一双鞋的里面。它是美洲原住民的一种传统鞋类，后来移民到这里的欧洲人也开始穿着莫卡辛鞋。语源学上，“moccasin”一词来自阿尔冈昆语族的波坦瓦语“makasin” （与马萨诸塞语“mohkisson /mokussin”、奥吉布瓦语“makizin”或密克马克语“mksɨn”同源），它们在原始阿尔冈昆语中为“maxkeseni”，意思就是“鞋”。

A moccasin is an outdoor slipper, made of moose skin or other soft leather, consisting of a sole (made with leather that has not been "worked") and sides made of one piece of leather, stitched together at the top, and sometimes with a vamp (additional panel of leather). The sole is soft and flexible and the upper part often is adorned with embroidery or beading. Though sometimes worn inside, it is chiefly intended for outdoor use, as in exploring wildernesses and running. Historically, it is the footwear of many indigenous peoples of North America; moreover, hunters, traders, and European settlers wore them. Etymologically, the moccasin derives from the Algonquian language Powhatan word makasin (cognate to Massachusett mohkisson / mokussin, Ojibwa makizin, Mi'kmaq mksɨn), and from the Proto-Algonquian word *maxkeseni (shoe).