KGF can specifically stimulate the epithelial mitogenesis and regulate the interaction of mesenchyma and epithelia,so it has broad biological functions. 角质细胞生长因子能特异性刺激上皮细胞有丝分裂,调节间质-上皮相互作用,有广泛的生物学功能。
A mitogen is a chemical substance that encourages a cell to commence cell division, triggering mitosis. A mitogen is usually some form of a protein. Mitogenesis is the induction (triggering) of mitosis, typically via a mitogen. Mitogens trigger signal transduction pathways in which mitogen-activated protein kinase (MAPK) is involved, leading to mitosis.