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词汇 Minisatellite repeats
分类 英语词汇 英语翻译词典
释义

Minisatellite repeats

中文百科

小卫星 Minisatellite

(重定向自Minisatellite repeats)

小卫星(英语:Minisatellite)或小卫星串行是一段含有约10到100个碱基对的DNA片段,在人类基因组中约出现在1000个以上的位置。某些小卫星串行含有一个核心串行“GGGCAGGAXG”(X表示任何字母),其他大多则是一股皆嘌呤,另一股皆嘧啶。在人体内,约90%的小卫星串行出现在靠近端粒的位置,端粒本身则主要是相连重复(tandem repeat)。

英语百科

Minisatellite 小卫星

(重定向自Minisatellite repeats)

A minisatellite is a tract of repetitive DNA in which certain DNA motifs (ranging in length from 10–60 base pairs) are typically repeated 5-50 times. Minisatellites occur at more than 1,000 locations in the human genome and they are notable for their high mutation rate and high diversity in the population. Minisatellites are prominent in the centromeres and telomeres of chromosomes, the latter protecting the chromosomes from damage. The name "satellite" refers to the early observation that centrifugation of genomic DNA in a test tube separates a prominent layer of bulk DNA from accompanying "satellite" layers of repetitive DNA.

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