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词汇 Membrane microdomains
分类 英语词汇 英语翻译词典
释义

Membrane microdomains

英语百科

Lipid raft

(重定向自Membrane microdomains)
Lipid raft organisation, region (1) is standard lipid bilayer, while region (2) is a lipid raft.
Space-filling models of sphingomyelin (a) and cholesterol (b).
IgE signalling process
T-cell antigen receptor signalling process

The plasma membranes of cells contain combinations of glycosphingolipids and protein receptors organized in glycolipoprotein microdomains termed lipid rafts. These specialized membrane microdomains compartmentalize cellular processes by serving as organizing centers for the assembly of signaling molecules, influencing membrane fluidity and membrane protein trafficking, and regulating neurotransmission and receptor trafficking. Lipid rafts are more ordered and tightly packed than the surrounding bilayer, but float freely in the membrane bilayer. Although more common in plasma membrane, lipid rafts have also been reported in other parts of the cell, such as the Golgi apparatus and lysosomes.

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