马赛皂（法语：Savon de Marseille）是一种清洁能力很强，用于身体保湿的香皂。它是通过精炼植物油以及氢氧化钠进行皂化反应得出的产品。这种产品可以通过工业流水线或者手工制作完成。传统马赛皂的一项必要指标就是其必须含有仅从橄榄油中制得的72%的脂肪酸。

在十七世纪，法国的路易十四规定了这种香皂的制作标准。到了十九世纪，马赛地区拥有90家制皂厂，这个兴盛的产业处于化学领域的前列。1913年其产量达到18万吨，攀上巅峰。1950年以后，主流清洁剂的迅猛发展则加速了马赛皂的衰败。

Marseille soap or Savon de Marseille is a traditional hard soap made from vegetable oils that has been produced around Marseille, France, for about 600 years. The first documented soapmaker was recorded there in about 1370. By 1688, Louis XIV introduced regulations in the Edict of Colbert limiting the use of the name savon de Marseille to olive oil based soaps. The law has since been amended to allow other vegetable oils to be used.