Mantle zone
![](/Images/godic/202501/25/Keimzentrum5736.jpg")
![Intermediate magnification micrograph of Castleman disease showing the characteristic expansion of the mantle zone. H&E stain.](/Images/godic/202501/25/Castleman_disease_-_intermed_mag5736.jpg")
The mantle zone (or just mantle) of a lymphatic nodule (or lymphatic follicle) is an outer ring of small lymphocytes surrounding a germinal center.
It is also known as the "corona".
It contains transient lymphocytes.
It is the location of the lymphoma in mantle cell lymphoma.