Malesco is a comune (municipality) in the Province of Verbano-Cusio-Ossola in the Italian region Piedmont, located about 130 kilometres (81mi) northeast of Turin and about 20 kilometres (12mi) north of Verbania, the provincial capital. As of 31 December 2004, it had a population of 1,478 and an area of 43.2 square kilometres (16.7sqmi).