Lukusuzi National Park is located in eastern Luangwa Valley in Zambia, on the other side of the Luangwa River from the more famous South Luangwa National Park. It lies between the smaller Luambe National Park (on the eastern bank of the river) and the Chipata-Lundazi road. Much of the park is plateau dissected by rocky ridges and rugged valleys. The main ecoregion in which the park lies is the southern miombo woodlands characterised by the miombo trees insterspersed with grassland. At lower elevations, such as at the bottom of the Luangwa valley, miombo give way to mopane trees.