Loiano is a town and comune of province of Bologna in the Emilia-Romagna region of Italy in the Tusco-Emilian Apennines at 714 metres (2,343ft) above sea level. Its population was 4,260 as of the 2003 census. Highway SS65 connects it to Bologna, 35 kilometres (22mi) to the north, and Florence, 73 kilometres (45mi) to the south.