Liver sinusoid

A liver sinusoid is a type of sinusoidal blood vessel (with fenestrated, discontinuous endothelium) that serves as a location for mixing of the oxygen-rich blood from the hepatic artery and the nutrient-rich blood from the portal vein.

Hepatocytes are separated from the sinusoids by the space of Disse. Kupffer cells are located inside the sinusoids and can take up and destroy foreign material such as bacteria.