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The city of Limpio (formerly known as Tapúa) is located in the Central Department, Paraguay. It was founded on February 2, 1785, by the Friar Luís de Bolaños under the name of San José de los Campos Limpios de Tapúa.

It was one of the first centers of Spanish–Guaraní crossbreeding. It is bordered by three rivers: The Paraguay River, the Salado River and the San Francisco River. Its saint patron is Saint Joseph.