Clozapine
（重定向自Leponex）
![Skeletal formula of clozapine](/Images/godic/202501/23/Clozapine.svg4522.png")
![Stick-and-ball model of the clozapine molecule](/Images/godic/202501/23/Clozapine_3D_ball4522.png")
![N-desmethylclozapine (norclozapine), clozapine's chief active metabolite](/Images/godic/202501/23/Desmethylclozapine.svg4522.png")
Clozapine, sold under the brand name Clozaril among others, is an atypical antipsychotic medication. It is mainly used for schizophrenia that does not improve following the use of other antipsychotic medications. In those with schizophrenia and schizoaffective disorder it may decrease the rate of suicidal behavior. It is possibly more effective than typical antipsychotics. It is taken by mouth.