The level of uncertainty, the absence of absolutes, has probably never been greater.这种充满变数、毫无把握的情形很可能前所未有。Investing his savings in that dubious stock was disastrous.他把积蓄投资于那毫无把握的股票是灾难性的一搏。Finding a house in London is a lottery even at the best of times.即使在情况最好的时候，在伦敦找房子也是一件毫无把握的事。