Saquinavir
（重定向自Invirase）
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![HIV deaths in the United States fell from approximately 50,000 per year to 18,000 in the two years following the FDA approval of saquinavir[9]](/Images/godic/202501/20/HIV_new_infections_and_deaths_1981-20084525.jpg")
Saquinavir, sold under the brand names Invirase and Fortovase, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS. Typically it is used with ritonavir or lopinavir/ritonavir. It is taken by mouth.
Common side effects include nausea, vomiting, diarrhea, and feeling tired. More serious side effects include problems with QT prolongation, heart block, high blood lipids, and liver problems. It appears to be safe in pregnancy. It is in the protease inhibitor class and works by blocking the HIV protease.