Hexane /ˈhɛkseɪn/ is an alkane of six carbon atoms, with the chemical formula C₆H₁₄.

The term may refer to any of the five structural isomers with that formula, or to a mixture of them. In IUPAC nomenclature, however, hexane is the unbranched isomer (n-hexane); the other four isomers are named as methylated derivatives of pentane and butane. IUPAC also uses the term as the root of many compounds with a linear six-carbon backbone, such as 2-methylhexane (C₇H₁₆), which is also called "isoheptane".