Hedgehog signaling pathway
![Figure 1. Normal and Hedgehog mutant larvae.](/Images/godic/202501/17/Denticlebands0244.png")
![Figure 2. Production of the CiR transcriptional repressor when Hh is not bound to Patched. In the diagram,](/Images/godic/202501/17/HedgehogCiR.svg0244.png")
![Figure 3. When Hh is bound to Patched (PTCH), Ci protein is able to act as a transcription factor in the nucleus.](/Images/godic/202501/17/HedgehogActive.svg0245.png")
![Figure 4. Interactions between Wingless and Hedgehog.](/Images/godic/202501/17/Wingless_and_Hedgehog_reciprocal_signaling_during_segmentation_of_Drosophila_embryos.svg0245.png")
The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper development. Different parts of the embryo have different concentrations of hedgehog signaling proteins. The pathway also has roles in the adult. Diseases associated with the malfunction of this pathway include basal cell carcinoma.