Guxhagen is a community in Schwalm-Eder district in northern Hesse, Germany.
Guxhagen lies about 15km south of Kassel between the Habichtswald Nature Park and the Meißner-Kaufunger Wald Nature Park on the river Fulda. It neighbors Edermünde, Felsberg, Fuldabrück and Körle. The community consists of the six centers of Albshausen, Büchenwerra, Ellenberg, Grebenau, Guxhagen and Wollrode.