Guardiagrele is a town and comune in the province of Chieti, part of the Abruzzo region of central Italy. It is in the foothills of the Maiella mountain at an elevation of around 576 metres (1,890 ft). Its population numbers about 10,000.

Captivated by the beauty of the panoramic views of the mountains and valleys of the Maiella visible from some points in the town, the poet Gabriele d'Annunzio nicknamed Guardiagrele 'la terrazza d'Abruzzo ("Abruzzo's terrace").