In Prader-Willi, the hypothalamus has issues secreting gonadotropin releasing hormone and growth hormone releasing hormone as it should, which can cause decreased sex hormone levels and short stature, respectively.
在普拉德-威利综合征的发展中，下丘脑分泌促性腺激素释放激素和生长激素释放激素受阻，分别导致性腺激素分泌不足以及身材矮小。