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词汇 Gel permeation chromatography
分类 英语词汇 英语翻译词典
释义

Gel permeation chromatography

英语百科

Gel permeation chromatography

Schematic of pore vs. analyte size
Range of molecular weights that can be separated for each packing material
A typical GPC instrument including A. autosampler, B.Column C.Pump D. RI Detector E. UV-vis Detector
Inside of an autosampler for running several samples without user interaction, e.g. overnight

Gel permeation chromatography (GPC) is a type of size exclusion chromatography (SEC), that separates analytes on the basis of size. The technique is often used for the analysis of polymers. As a technique, SEC was first developed in 1955 by Lathe and Ruthven. The term gel permeation chromatography can be traced back to J.C. Moore of the Dow Chemical Company who investigated the technique in 1964 and the proprietary column technology was licensed to Waters Corporation, who subsequently commercialized this technology in 1964. GPC systems and consumables are now also available from a number of manufacturers. It is often necessary to separate polymers, both to analyze them as well as to purify the desired product.

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