法尼基转移酶（英语：Farnesyltransferase）是三种转异戊二烯酶(prenyltransferase)的其中一种。法尼基转移酶(FTase)是在蛋白质上加一个15个碳的萜烯而产生了一个CaaX的模段(motif)：一种在蛋白质C端的四个胺基酸串行。

法尼基转移酶的标的蛋白质包括对细胞周期进行很重要的small GTP-bindding protein中Ras superfamily的成员。因此，许多将法尼基转移酶抑制剂开发成抗癌药的试验正进行着。法尼基转移酶抑制剂在对抗寄生虫方面也有不错的效果。也有人相信FTase在早老症(早年衰老症候群，progeria)和许多癌症的病程上扮演着重要的角色。

Farnesyltransferase (EC2.5.1.58) is one of the three enzymes in the prenyltransferase group. Farnesyltransferase (FTase) adds a 15-carbon isoprenoid called a farnesyl group to proteins bearing a CaaX motif: a four-amino acid sequence at the carboxyl terminus of a protein. Farnesyltransferase's targets include members of the Ras superfamily of small GTP-binding proteins critical to cell cycle progression. For this reason, several FTase inhibitors are undergoing testing as anti-cancer agents. FTase inhibitors have shown efficacy as anti-parasitic agents, as well. FTase is also believed to play an important role in development of progeria and various forms of cancers.