Francofonte (Sicilian: Francufonti) is a comune (municipality) in the Province of Syracuse, Sicily, southern Italy, located about 170 kilometres (110mi) southeast of Palermo and about 40 kilometres (25mi) northwest of Syracuse.
Francofonte borders the following municipalities: Buccheri, Carlentini, Lentini, Militello in Val di Catania, Scordia, Vizzini.