Edisto Beach is a town in Colleton County, South Carolina, United States. Edisto Beach's population was 414 as of the 2010 census, down from 641 at the 2000 census. The town limits include only the developed coastal area of Edisto Island within Colleton County, while the majority of the island consists of unincorporated land in Charleston County. Due to its status as a bedroom community, Edisto Beach is among the most affluent communities in the state.