Echinostoma hortense is an intestinal fluke of the class Trematoda, which has been found to infect humans in East Asian countries such as Korea, China, and Japan. This parasite resides in the intestines of birds, rats and other mammals such as humans. While human infections are very rare in other regions of the world, East Asian countries have reported human infections up to about 24% of the population in some endemic sub-regions. E. hortense infections are zoonotic infections, which occurs from eating raw or undercooked freshwater fish. The primary disease associated with an E. hortense infection is called echinostomiasis, which is a general name given to diseases caused by Trematodes of the genus Echinostoma.