3,4-Dihydroxyphenylacetic acid

（重定向自DOPAC）

3,4-Dihydroxyphenylacetic acid (DOPAC) is a metabolite of the neurotransmitter dopamine.

Dopamine can be metabolized into one of three substances. One such substance is DOPAC. Another is 3-methoxytyramine (3-MT). Both of these substances are degraded to form homovanillic acid (HVA). Both degradations involve the enzymes monoamine oxidase (MAO) and catechol-O-methyl transferase (COMT), albeit in reverse order: MAO catalyzes dopamine to DOPAC, and COMT catalyzes DOPAC to HVA; whereas COMT catalyzes dopamine to 3-MT and MAO catalyzes 3-MT to HVA. The third metabolic end-product of dopamine is norepinephrine (noradrenaline).

词汇	DOPAC
分类	英语词汇英语翻译词典
释义	DOPAC 原声例句医学英语视频 However, lets not forget that dopamine is also susceptible to breakdown by COMT as well as MAO-B, which convert dopamine to 3-methoxytyramine (3-MT) and 3,4dihydroxyphenylacetic acid (DOPAC) respectively. 然而，我们不要忘记多巴胺也容易被COMT分解如MAO-B，可将多巴胺转化为3-甲氧基酪胺（3-MT）和3，4-二羟基苯乙酸（DOPAC）分别。英语百科 3,4-Dihydroxyphenylacetic acid （重定向自DOPAC） 3,4-Dihydroxyphenylacetic acid (DOPAC) is a metabolite of the neurotransmitter dopamine. Dopamine can be metabolized into one of three substances. One such substance is DOPAC. Another is 3-methoxytyramine (3-MT). Both of these substances are degraded to form homovanillic acid (HVA). Both degradations involve the enzymes monoamine oxidase (MAO) and catechol-O-methyl transferase (COMT), albeit in reverse order: MAO catalyzes dopamine to DOPAC, and COMT catalyzes DOPAC to HVA; whereas COMT catalyzes dopamine to 3-MT and MAO catalyzes 3-MT to HVA. The third metabolic end-product of dopamine is norepinephrine (noradrenaline).
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