Hsp70
![](/Images/godic/202501/09/PDB_3hsc_EBI1322.jpg")
![Hsp70 (pdb database 2KHO). Left domain is NBD (Nucleotide Binding domain) which can bind to ATP and ADP. Right lower domain is the groove, Subtrate Binding domain. Right upper domain is the](/Images/godic/202501/09/Hsp70_Overview1322.png")
The 70 kilodalton heat shock proteins (Hsp70s) are a family of conserved ubiquitously expressed heat shock proteins. Proteins with similar structure exist in virtually all living organisms. The Hsp70s are an important part of the cell's machinery for protein folding, and help to protect cells from stress.