膜增生性肾小球肾炎 Membranoproliferative glomerulonephritis
（重定向自Dense deposit disease）
![](/Images/godic/202501/08/Membranoproliferative_glomerulonephritis_-_very_high_mag5518.jpg")
膜增生性肾小球肾炎(Membranoproliferative glomerulonephritis、MPGN)，也被称为"系膜毛细管性肾小球肾炎"(mesangiocapillary glomerulonephritis)， 是一种类型的肾小球肾炎引起的肾脏"肾小球系膜及基底膜(GBM)"增厚沉积，激活补体系统和破坏肾小球。
MPGN之肾炎综合征的"原发性肾起因"(primary renal cause)于儿童约占4％而成年人约7％。
它不应该与膜性肾小球肾炎相混淆，"膜性肾小球肾炎"是处于基底膜增厚的状态下，而其系膜是没有此种情况的。
![Renal corpuscle. Membranoproliferative glomerulonephritis involves deposits at the intraglomerular mesangium (#5a) which leads to](/Images/godic/202501/08/Renal_corpuscle.svg5518.png")
![Enfermedades por complejos inmunes. Large complex: complejo de gran tamaño. Endothelial cell: célula endotelial. Glomerular basement membrane of kidney: membrana basal glomerular renal. Small complex: complejo pequeño.](/Images/godic/202501/08/Immune225518.gif")
![El endotelio tapiza la pared interna de los vasos sanguíneos. Continuous: continuo. Fenestrated: con fenestraciones. Sinusoid: sinusoidal. Basement membrane: membrana basal. Intercellular cleft: hendidura intercelular. Fenestrations: fenestraciones. Intercellular gap: brecha intercelular. Incomplete basement membrane: membrana basal incompleta.](/Images/godic/202501/08/2104_Three_Major_Capillary_Types5518.jpg")