Those people have been waiting for hours, and they're starting to run out of patience. = They're starting to lose patience.那些人已经等了几个小时，他们开始失去耐心。I'm beginning to lose patience with you people.我开始对你们这些人失去耐心了。Try not to lose patience with the children.尽量不要对孩子失去耐心。I'm beginning to lose patience with you and your feeble excuses.我开始对你和你那些牵强的借口失去耐性了。