Aldosterone synthase
（重定向自CYP11B2）
![](/Images/godic/202501/07/Aldosteronecomplexdeoxycorticosterone2630.jpg")
![](/Images/godic/202501/07/PBB_GE_CYP11B2_214630_at_tn2630.png")
![Renin-angiotensin system schematic showing aldosterone activity on the right](/Images/godic/202501/07/Renin-angiotensin-aldosterone_system2630.png")
![Biosynthetic pathway of aldosterone starting with progesterone](/Images/godic/202501/07/ALDOSTERONESynthesis.svg2630.png")
Aldosterone synthase is a steroid hydroxylase cytochrome P450 enzyme involved in the biosynthesis of the mineralocorticoid aldosterone. It is a protein which is only expressed in the zona glomerulosa of the adrenal cortex and is primarily regulated by the renin-angiotensin system. It is the sole enzyme capable of synthesizing aldosterone in humans and plays an important role in electrolyte balance and blood pressure.